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A control system analysis of the dynamic response of N-methyl-D-aspartate glutamate receptors to alcoholism and alcohol withdrawal

BACKGROUND: N-methyl-D-Aspartate (NMDA) and its receptors (NMDAR) play a critical role in glutamatergic neurotransmission. Ethanol molecules inhibit these receptors, and if the brain is exposed to ethanol chronically, NMDA-induced glutamatergic changes can result in physical dependence to ethanol in...

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Detalles Bibliográficos
Autores principales: Gutierrez, Carlos A, Staehle, Mary M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455702/
https://www.ncbi.nlm.nih.gov/pubmed/25982851
http://dx.doi.org/10.1186/s12976-015-0004-3