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Genome-wide Screens for Sensitivity to Ionizing Radiation Identify the Fission Yeast Nonhomologous End Joining Factor Xrc4

Nonhomologous end joining (NHEJ) is the main means for repairing DNA double-strand breaks (DSBs) in human cells. Molecular understanding of NHEJ has benefited from analyses in the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe. In human cells, the DNA ligation...

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Detalles Bibliográficos
Autores principales:	Li, Jun, Yu, Yang, Suo, Fang, Sun, Ling-Ling, Zhao, Dan, Du, Li-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2014
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455778/ https://www.ncbi.nlm.nih.gov/pubmed/24847916 http://dx.doi.org/10.1534/g3.114.011841

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