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Selective observation of the disordered import signal of a globular protein by in-cell NMR: The example of frataxins

We have exploited the capability of in-cell NMR to selectively observe flexible regions within folded proteins to carry out a comparative study of two members of the highly conserved frataxin family which are found both in prokaryotes and in eukaryotes. They all contain a globular domain which share...

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Detalles Bibliográficos
Autores principales: Popovic, Matija, Sanfelice, Domenico, Pastore, Chiara, Prischi, Filippo, Temussi, Piero Andrea, Pastore, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456112/
https://www.ncbi.nlm.nih.gov/pubmed/25772583
http://dx.doi.org/10.1002/pro.2679

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