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Distinct Clinicopathological Patterns of Mismatch Repair Status in Colorectal Cancer Stratified by KRAS Mutations

In sporadic colorectal cancer (CRC), the BRAF(V600E) mutation is associated with deficient mismatch repair (MMR) status and inversely associated with to KRAS mutations. In contrast to deficient MMR (dMMR) CRC, data on the presence of KRAS oncogenic mutations in proficient MMR (pMMR) CRC and their re...

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Detalles Bibliográficos
Autores principales:	Li, Wenbin, Zhi, Wenxue, Zou, Shuangmei, Qiu, Tian, Ling, Yun, Shan, Ling, Shi, Susheng, Ying, Jianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456280/ https://www.ncbi.nlm.nih.gov/pubmed/26042813 http://dx.doi.org/10.1371/journal.pone.0128202

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