A Novel 1,4-Dihydropyridine Derivative Improves Spatial Learning and Memory and Modifies Brain Protein Expression in Wild Type and Transgenic APP(SweDI) Mice

Ca(2+) blockers, particularly those capable of crossing the blood-brain barrier (BBB), have been suggested as a possible treatment or disease modifying agents for neurodegenerative disorders, e.g., Alzheimer’s disease. The present study investigated the effects of a novel 4-(N-dodecyl) pyridinium gr...

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Detalles Bibliográficos
Autores principales: Jansone, Baiba, Kadish, Inga, van Groen, Thomas, Beitnere, Ulrika, Moore, Doyle Ray, Plotniece, Aiva, Pajuste, Karlis, Klusa, Vija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456351/
https://www.ncbi.nlm.nih.gov/pubmed/26042808
http://dx.doi.org/10.1371/journal.pone.0127686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456351/
https://www.ncbi.nlm.nih.gov/pubmed/26042808
http://dx.doi.org/10.1371/journal.pone.0127686

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