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Antitumor Activity of a 5-Hydroxy-1H-Pyrrol-2-(5H)-One-Based Synthetic Small Molecule In Vitro and In Vivo

Alternative chemo-reagents are in great demand because chemotherapy resistance is one of the major challenges in current cancer treatment. 5-hydoxy-1H-pyrrol-2-(5H)-one is an important N-heterocyclic scaffold that is present in natural products and medicinal chemistry. However, its antitumor activit...

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Detalles Bibliográficos
Autores principales:	Geng, Yunyun, Wang, Xiaojian, Yang, Luo, Sun, Haili, Wang, Yongqiang, Zhao, Yue, She, Ruiping, Wang, Mei-Xiang, Wang, De-Xian, Tang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456381/ https://www.ncbi.nlm.nih.gov/pubmed/26042776 http://dx.doi.org/10.1371/journal.pone.0128928

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