An efficient and selective microwave-assisted Claisen-Schmidt reaction for the synthesis of functionalized benzalacetones

A simple and direct method for the Claisen-Schmidt reaction to prepare functionalized α,β-unsaturated ketones has been developed. Microwave irradiation of aldehydes with acetone produces benzalacetones selectively without self-condensation product in very short reaction times and good yields. [Figur...

Descripción completa

Detalles Bibliográficos
Autores principales: Rayar, Anita, Veitía, Maité Sylla-Iyarreta, Ferroud, Clotilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456587/
https://www.ncbi.nlm.nih.gov/pubmed/26069871
http://dx.doi.org/10.1186/s40064-015-0985-8
_version_ 1782374853090738176
author Rayar, Anita
Veitía, Maité Sylla-Iyarreta
Ferroud, Clotilde
author_facet Rayar, Anita
Veitía, Maité Sylla-Iyarreta
Ferroud, Clotilde
author_sort Rayar, Anita
collection PubMed
description A simple and direct method for the Claisen-Schmidt reaction to prepare functionalized α,β-unsaturated ketones has been developed. Microwave irradiation of aldehydes with acetone produces benzalacetones selectively without self-condensation product in very short reaction times and good yields. [Figure: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40064-015-0985-8) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-4456587
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-44565872015-06-11 An efficient and selective microwave-assisted Claisen-Schmidt reaction for the synthesis of functionalized benzalacetones Rayar, Anita Veitía, Maité Sylla-Iyarreta Ferroud, Clotilde Springerplus Research A simple and direct method for the Claisen-Schmidt reaction to prepare functionalized α,β-unsaturated ketones has been developed. Microwave irradiation of aldehydes with acetone produces benzalacetones selectively without self-condensation product in very short reaction times and good yields. [Figure: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40064-015-0985-8) contains supplementary material, which is available to authorized users. Springer International Publishing 2015-05-14 /pmc/articles/PMC4456587/ /pubmed/26069871 http://dx.doi.org/10.1186/s40064-015-0985-8 Text en © Rayar et al.; licensee Springer. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Research
Rayar, Anita
Veitía, Maité Sylla-Iyarreta
Ferroud, Clotilde
An efficient and selective microwave-assisted Claisen-Schmidt reaction for the synthesis of functionalized benzalacetones
title An efficient and selective microwave-assisted Claisen-Schmidt reaction for the synthesis of functionalized benzalacetones
title_full An efficient and selective microwave-assisted Claisen-Schmidt reaction for the synthesis of functionalized benzalacetones
title_fullStr An efficient and selective microwave-assisted Claisen-Schmidt reaction for the synthesis of functionalized benzalacetones
title_full_unstemmed An efficient and selective microwave-assisted Claisen-Schmidt reaction for the synthesis of functionalized benzalacetones
title_short An efficient and selective microwave-assisted Claisen-Schmidt reaction for the synthesis of functionalized benzalacetones
title_sort efficient and selective microwave-assisted claisen-schmidt reaction for the synthesis of functionalized benzalacetones
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456587/
https://www.ncbi.nlm.nih.gov/pubmed/26069871
http://dx.doi.org/10.1186/s40064-015-0985-8
work_keys_str_mv AT rayaranita anefficientandselectivemicrowaveassistedclaisenschmidtreactionforthesynthesisoffunctionalizedbenzalacetones
AT veitiamaitesyllaiyarreta anefficientandselectivemicrowaveassistedclaisenschmidtreactionforthesynthesisoffunctionalizedbenzalacetones
AT ferroudclotilde anefficientandselectivemicrowaveassistedclaisenschmidtreactionforthesynthesisoffunctionalizedbenzalacetones
AT rayaranita efficientandselectivemicrowaveassistedclaisenschmidtreactionforthesynthesisoffunctionalizedbenzalacetones
AT veitiamaitesyllaiyarreta efficientandselectivemicrowaveassistedclaisenschmidtreactionforthesynthesisoffunctionalizedbenzalacetones
AT ferroudclotilde efficientandselectivemicrowaveassistedclaisenschmidtreactionforthesynthesisoffunctionalizedbenzalacetones

Ejemplares similares