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A Novel Lung Explant Model for the Ex Vivo Study of Efficacy and Mechanisms of Anti-Influenza Drugs
Influenza A virus causes considerable morbidity and mortality largely because of a lack of effective antiviral drugs. Viral neuraminidase inhibitors, which inhibit viral release from the infected cell, are currently the only approved drugs for influenza, but have recently been shown to be less effec...
Autores principales: | Nicholas, Ben, Staples, Karl J., Moese, Stefan, Meldrum, Eric, Ward, Jon, Dennison, Patrick, Havelock, Tom, Hinks, Timothy S. C., Amer, Khalid, Woo, Edwin, Chamberlain, Martin, Singh, Neeta, North, Malcolm, Pink, Sandy, Wilkinson, Tom M. A., Djukanović, Ratko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456633/ https://www.ncbi.nlm.nih.gov/pubmed/25934861 http://dx.doi.org/10.4049/jimmunol.1402283 |
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