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Suramin inhibits cell proliferation in ovarian and cervical cancer by downregulating heparanase expression

BACKGROUND: Aberrant expression of heparanase (Hpa) is associated with apoor prognosis in ovarian and cervical cancer patients. Inhibitors of Hpa can prevent the growth and metastasis of malignant tumor cells, and suramin may be such a compound that has strong anti-proliferative effects on several k...

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Detalles Bibliográficos
Autores principales:	Li, HuaPing, Li, HuaLi, Qu, HongJie, Zhao, MingZhu, Yuan, Bo, Cao, MingHua, Cui, JinQuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456706/ https://www.ncbi.nlm.nih.gov/pubmed/26052253 http://dx.doi.org/10.1186/s12935-015-0196-y

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