Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)

Sinusoidal obstruction syndrome or veno-occlusive disease (SOS/VOD) is a potentially life-threatening complication of hematopoietic SCT (HSCT). This review aims to highlight, on behalf of the European Society for Blood and Marrow Transplantation, the current knowledge on SOS/VOD pathophysiology, ris...

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Autores principales: Mohty, M, Malard, F, Abecassis, M, Aerts, E, Alaskar, A S, Aljurf, M, Arat, M, Bader, P, Baron, F, Bazarbachi, A, Blaise, D, Ciceri, F, Corbacioglu, S, Dalle, J-H, Duarte, R F, Fukuda, T, Huynh, A, Masszi, T, Michallet, M, Nagler, A, NiChonghaile, M, Pagluica, T, Peters, C, Petersen, F B, Richardson, P G, Ruutu, T, Savani, B N, Wallhult, E, Yakoub-Agha, I, Carreras, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Special Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456788/
https://www.ncbi.nlm.nih.gov/pubmed/25798682
http://dx.doi.org/10.1038/bmt.2015.52
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author Mohty, M
Malard, F
Abecassis, M
Aerts, E
Alaskar, A S
Aljurf, M
Arat, M
Bader, P
Baron, F
Bazarbachi, A
Blaise, D
Ciceri, F
Corbacioglu, S
Dalle, J-H
Duarte, R F
Fukuda, T
Huynh, A
Masszi, T
Michallet, M
Nagler, A
NiChonghaile, M
Pagluica, T
Peters, C
Petersen, F B
Richardson, P G
Ruutu, T
Savani, B N
Wallhult, E
Yakoub-Agha, I
Carreras, E
author_facet Mohty, M
Malard, F
Abecassis, M
Aerts, E
Alaskar, A S
Aljurf, M
Arat, M
Bader, P
Baron, F
Bazarbachi, A
Blaise, D
Ciceri, F
Corbacioglu, S
Dalle, J-H
Duarte, R F
Fukuda, T
Huynh, A
Masszi, T
Michallet, M
Nagler, A
NiChonghaile, M
Pagluica, T
Peters, C
Petersen, F B
Richardson, P G
Ruutu, T
Savani, B N
Wallhult, E
Yakoub-Agha, I
Carreras, E
author_sort Mohty, M
collection PubMed
description Sinusoidal obstruction syndrome or veno-occlusive disease (SOS/VOD) is a potentially life-threatening complication of hematopoietic SCT (HSCT). This review aims to highlight, on behalf of the European Society for Blood and Marrow Transplantation, the current knowledge on SOS/VOD pathophysiology, risk factors, diagnosis and treatments. Our perspectives on SOS/VOD are (i) to accurately identify its risk factors; (ii) to define new criteria for its diagnosis; (iii) to search for SOS/VOD biomarkers and (iv) to propose prospective studies evaluating SOS/VOD prevention and treatment in adults and children.
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spelling pubmed-44567882015-06-19 Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT) Mohty, M Malard, F Abecassis, M Aerts, E Alaskar, A S Aljurf, M Arat, M Bader, P Baron, F Bazarbachi, A Blaise, D Ciceri, F Corbacioglu, S Dalle, J-H Duarte, R F Fukuda, T Huynh, A Masszi, T Michallet, M Nagler, A NiChonghaile, M Pagluica, T Peters, C Petersen, F B Richardson, P G Ruutu, T Savani, B N Wallhult, E Yakoub-Agha, I Carreras, E Bone Marrow Transplant Special Report Sinusoidal obstruction syndrome or veno-occlusive disease (SOS/VOD) is a potentially life-threatening complication of hematopoietic SCT (HSCT). This review aims to highlight, on behalf of the European Society for Blood and Marrow Transplantation, the current knowledge on SOS/VOD pathophysiology, risk factors, diagnosis and treatments. Our perspectives on SOS/VOD are (i) to accurately identify its risk factors; (ii) to define new criteria for its diagnosis; (iii) to search for SOS/VOD biomarkers and (iv) to propose prospective studies evaluating SOS/VOD prevention and treatment in adults and children. Nature Publishing Group 2015-06 2015-03-23 /pmc/articles/PMC4456788/ /pubmed/25798682 http://dx.doi.org/10.1038/bmt.2015.52 Text en Copyright © 2015 Macmillan Publishers Limited http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Special Report
Mohty, M
Malard, F
Abecassis, M
Aerts, E
Alaskar, A S
Aljurf, M
Arat, M
Bader, P
Baron, F
Bazarbachi, A
Blaise, D
Ciceri, F
Corbacioglu, S
Dalle, J-H
Duarte, R F
Fukuda, T
Huynh, A
Masszi, T
Michallet, M
Nagler, A
NiChonghaile, M
Pagluica, T
Peters, C
Petersen, F B
Richardson, P G
Ruutu, T
Savani, B N
Wallhult, E
Yakoub-Agha, I
Carreras, E
Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)
title Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)
title_full Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)
title_fullStr Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)
title_full_unstemmed Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)
title_short Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)
title_sort sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the european society for blood and marrow transplantation (ebmt)
topic Special Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456788/
https://www.ncbi.nlm.nih.gov/pubmed/25798682
http://dx.doi.org/10.1038/bmt.2015.52
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