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PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation

BACKGROUND: p21-activated kinase 1 (PAK1) is a serine/threonine kinase known to be activated by the Rho family small GTPases and to play a key role in cytoskeletal reorganization, spine morphology and synaptic plasticity. PAK1 is also implicated in a number of neurodevelopmental and neurodegenerativ...

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Detalles Bibliográficos
Autores principales:	Pan, Xingxiu, Chang, Xinxia, Leung, Celeste, Zhou, Zikai, Cao, Feng, Xie, Wei, Jia, Zhengping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456803/ https://www.ncbi.nlm.nih.gov/pubmed/26043730 http://dx.doi.org/10.1186/s13041-015-0124-z

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