Phentermine-topiramate: First combination drug for obesity

Obesity is spreading globally at an alarming speed. The management of obesity is multifaceted and includes lifestyle modifications as the cornerstone. Until only orlistat was approved for long term use in obesity. The US Food and Drug Administration granted approval to a fixed dose mid 2012 combinat...

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Detalles Bibliográficos
Autores principales: Singh, Jagjit, Kumar, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
New Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456896/
https://www.ncbi.nlm.nih.gov/pubmed/26097830
http://dx.doi.org/10.4103/2229-516X.157177
Descripción
Sumario:Obesity is spreading globally at an alarming speed. The management of obesity is multifaceted and includes lifestyle modifications as the cornerstone. Until only orlistat was approved for long term use in obesity. The US Food and Drug Administration granted approval to a fixed dose mid 2012 combination of phentermine immediate release and topiramate extended release in 2012 for treatment of obese patients or overweight patients with comorbid conditions. The new drug has shown significant weight loss compared with placebo for a period up to 2 years.

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