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The Ca(2+)-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy

Cardiac muscle adapts to hemodynamic stress by altering myocyte size and function, resulting in cardiac hypertrophy. Alteration in myocyte calcium homeostasis is known to be an initial signal in cardiac hypertrophy signaling. Transient receptor potential melastatin 4 protein (TRPM4) is a calcium-act...

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Detalles Bibliográficos
Autores principales: Kecskés, Miklós, Jacobs, Griet, Kerselaers, Sara, Syam, Ninda, Menigoz, Aurélie, Vangheluwe, Peter, Freichel, Marc, Flockerzi, Veit, Voets, Thomas, Vennekens, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456993/
https://www.ncbi.nlm.nih.gov/pubmed/26043922
http://dx.doi.org/10.1007/s00395-015-0501-x