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The Ca(2+)-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy
Cardiac muscle adapts to hemodynamic stress by altering myocyte size and function, resulting in cardiac hypertrophy. Alteration in myocyte calcium homeostasis is known to be an initial signal in cardiac hypertrophy signaling. Transient receptor potential melastatin 4 protein (TRPM4) is a calcium-act...
Autores principales: | Kecskés, Miklós, Jacobs, Griet, Kerselaers, Sara, Syam, Ninda, Menigoz, Aurélie, Vangheluwe, Peter, Freichel, Marc, Flockerzi, Veit, Voets, Thomas, Vennekens, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456993/ https://www.ncbi.nlm.nih.gov/pubmed/26043922 http://dx.doi.org/10.1007/s00395-015-0501-x |
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