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Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis
Mice are the most commonly used species for non-clinical evaluations of drug efficacy against tuberculosis (TB). Unlike commonly used strains, C3HeB/FeJ mice develop caseous necrosis in the lung, which might alter the representation of drug efficacy in a way that is more like human TB. Because the d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Company of Biologists
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457036/ https://www.ncbi.nlm.nih.gov/pubmed/26035868 http://dx.doi.org/10.1242/dmm.019513 |