The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain

BACKGROUND: Tumour metastasis to the brain is a common and deadly development in certain cancers; 18–30 % of breast tumours metastasise to the brain. The contribution that gene silencing through epigenetic mechanisms plays in these metastatic tumours is not well understood. RESULTS: We have carried...

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Detalles Bibliográficos
Autores principales: Pangeni, Rajendra P., Channathodiyil, Prasanna, Huen, David S., Eagles, Lawrence W., Johal, Balraj K., Pasha, Dawar, Hadjistephanou, Natasa, Nevell, Oliver, Davies, Claire L., Adewumi, Ayobami I., Khanom, Hamida, Samra, Ikroop S., Buzatto, Vanessa C., Chandrasekaran, Preethi, Shinawi, Thoraia, Dawson, Timothy P., Ashton, Katherine M., Davis, Charles, Brodbelt, Andrew R., Jenkinson, Michael D., Bièche, Ivan, Latif, Farida, Darling, John L., Warr, Tracy J., Morris, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457099/
https://www.ncbi.nlm.nih.gov/pubmed/26052355
http://dx.doi.org/10.1186/s13148-015-0089-x

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