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It's never too late to publish an abandoned trial

It is estimated that half of all trials have never been published which can lead to patients being denied the most effective treatment and being exposed to unnecessary side effects.  Furthermore the trial participants have been misinformed since the trial results have not contributed to the care of...

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Detalles Bibliográficos
Autores principales: Shiles, Celia, Sinclair, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457106/
https://www.ncbi.nlm.nih.gov/pubmed/26097695
http://dx.doi.org/10.12688/f1000research.6519.1
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author Shiles, Celia
Sinclair, Julia
author_facet Shiles, Celia
Sinclair, Julia
author_sort Shiles, Celia
collection PubMed
description It is estimated that half of all trials have never been published which can lead to patients being denied the most effective treatment and being exposed to unnecessary side effects.  Furthermore the trial participants have been misinformed since the trial results have not contributed to the care of future patients. However the non-publication of trials is often not due to a deliberate decision to cover up results.  Commonly in academia it is due to more understandable reasons such as researchers having busy clinical posts, moving onto other more demanding projects, changing research areas or starting a family.  This is called the “file drawer” problem. The examples in this editorial demonstrate that it is possible to go back, even decades later, and make the results available to inform future evidence based medicine.  We call on others to look into their “file drawer” for unpublished trials.
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spelling pubmed-44571062015-06-19 It's never too late to publish an abandoned trial Shiles, Celia Sinclair, Julia F1000Res Editorial It is estimated that half of all trials have never been published which can lead to patients being denied the most effective treatment and being exposed to unnecessary side effects.  Furthermore the trial participants have been misinformed since the trial results have not contributed to the care of future patients. However the non-publication of trials is often not due to a deliberate decision to cover up results.  Commonly in academia it is due to more understandable reasons such as researchers having busy clinical posts, moving onto other more demanding projects, changing research areas or starting a family.  This is called the “file drawer” problem. The examples in this editorial demonstrate that it is possible to go back, even decades later, and make the results available to inform future evidence based medicine.  We call on others to look into their “file drawer” for unpublished trials. F1000Research 2015-05-15 /pmc/articles/PMC4457106/ /pubmed/26097695 http://dx.doi.org/10.12688/f1000research.6519.1 Text en Copyright: © 2015 Shiles C and Sinclair J http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/publicdomain/zero/1.0/ Data associated with the article are available under the terms of the Creative Commons Zero "No rights reserved" data waiver (CC0 1.0 Public domain dedication).
spellingShingle Editorial
Shiles, Celia
Sinclair, Julia
It's never too late to publish an abandoned trial
title It's never too late to publish an abandoned trial
title_full It's never too late to publish an abandoned trial
title_fullStr It's never too late to publish an abandoned trial
title_full_unstemmed It's never too late to publish an abandoned trial
title_short It's never too late to publish an abandoned trial
title_sort it's never too late to publish an abandoned trial
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457106/
https://www.ncbi.nlm.nih.gov/pubmed/26097695
http://dx.doi.org/10.12688/f1000research.6519.1
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