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It's never too late to publish an abandoned trial
It is estimated that half of all trials have never been published which can lead to patients being denied the most effective treatment and being exposed to unnecessary side effects. Furthermore the trial participants have been misinformed since the trial results have not contributed to the care of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457106/ https://www.ncbi.nlm.nih.gov/pubmed/26097695 http://dx.doi.org/10.12688/f1000research.6519.1 |
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author | Shiles, Celia Sinclair, Julia |
author_facet | Shiles, Celia Sinclair, Julia |
author_sort | Shiles, Celia |
collection | PubMed |
description | It is estimated that half of all trials have never been published which can lead to patients being denied the most effective treatment and being exposed to unnecessary side effects. Furthermore the trial participants have been misinformed since the trial results have not contributed to the care of future patients. However the non-publication of trials is often not due to a deliberate decision to cover up results. Commonly in academia it is due to more understandable reasons such as researchers having busy clinical posts, moving onto other more demanding projects, changing research areas or starting a family. This is called the “file drawer” problem. The examples in this editorial demonstrate that it is possible to go back, even decades later, and make the results available to inform future evidence based medicine. We call on others to look into their “file drawer” for unpublished trials. |
format | Online Article Text |
id | pubmed-4457106 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | F1000Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-44571062015-06-19 It's never too late to publish an abandoned trial Shiles, Celia Sinclair, Julia F1000Res Editorial It is estimated that half of all trials have never been published which can lead to patients being denied the most effective treatment and being exposed to unnecessary side effects. Furthermore the trial participants have been misinformed since the trial results have not contributed to the care of future patients. However the non-publication of trials is often not due to a deliberate decision to cover up results. Commonly in academia it is due to more understandable reasons such as researchers having busy clinical posts, moving onto other more demanding projects, changing research areas or starting a family. This is called the “file drawer” problem. The examples in this editorial demonstrate that it is possible to go back, even decades later, and make the results available to inform future evidence based medicine. We call on others to look into their “file drawer” for unpublished trials. F1000Research 2015-05-15 /pmc/articles/PMC4457106/ /pubmed/26097695 http://dx.doi.org/10.12688/f1000research.6519.1 Text en Copyright: © 2015 Shiles C and Sinclair J http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/publicdomain/zero/1.0/ Data associated with the article are available under the terms of the Creative Commons Zero "No rights reserved" data waiver (CC0 1.0 Public domain dedication). |
spellingShingle | Editorial Shiles, Celia Sinclair, Julia It's never too late to publish an abandoned trial |
title | It's never too late to publish an abandoned trial |
title_full | It's never too late to publish an abandoned trial |
title_fullStr | It's never too late to publish an abandoned trial |
title_full_unstemmed | It's never too late to publish an abandoned trial |
title_short | It's never too late to publish an abandoned trial |
title_sort | it's never too late to publish an abandoned trial |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457106/ https://www.ncbi.nlm.nih.gov/pubmed/26097695 http://dx.doi.org/10.12688/f1000research.6519.1 |
work_keys_str_mv | AT shilescelia itsnevertoolatetopublishanabandonedtrial AT sinclairjulia itsnevertoolatetopublishanabandonedtrial |