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A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules
The accelerated discovery of disease-related genes emerging from genomic studies has strained the capacity of traditional genetically engineered mouse models (GEMMs) to provide in-vivo validation. Direct, somatic, genetic engineering approaches allow for accelerated and flexible genetic manipulation...
Autores principales: | Espana-Agusti, Judit, Tuveson, David A., Adams, David J., Matakidou, Athena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457145/ https://www.ncbi.nlm.nih.gov/pubmed/26046460 http://dx.doi.org/10.1038/srep11061 |
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