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Baicalein increases the expression and reciprocal interplay of RUNX3 and FOXO3a through crosstalk of AMPKα and MEK/ERK1/2 signaling pathways in human non-small cell lung cancer cells

BACKGROUND: Baicalein, a natural flavonoid obtained from the Scutellaria baicalensis root, has been reported to inhibit growth of human lung cancer. However, the detailed mechanism underlying this has not been well elucidated. METHODS: Cell viability was measured using a 3-(4, 5-dimethylthiazol-2-yl...

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Detalles Bibliográficos
Autores principales:	Zheng, Fang, Wu, Jingjing, Zhao, Shunyu, Luo, Qingmei, Tang, Qing, Yang, LiJun, Li, Liuning, Wu, WanYing, Hann, Swei Sunny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457308/ https://www.ncbi.nlm.nih.gov/pubmed/25948105 http://dx.doi.org/10.1186/s13046-015-0160-7

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