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Swertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo Study

Transplanting islets serves best option for restoring lost beta cell mass and function. Small bio-chemical agents do have the potential to generate new islets mass, however lack of understanding about mechanistic action of these small molecules eventually restricts their use in cell-based therapies...

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Detalles Bibliográficos
Autores principales: Dadheech, Nidheesh, Srivastava, Abhay, Paranjape, Neha, Gupta, Shivika, Dave, Arpita, Shah, Girish M., Bhonde, Ramesh R., Gupta, Sarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457488/
https://www.ncbi.nlm.nih.gov/pubmed/26047129
http://dx.doi.org/10.1371/journal.pone.0128244