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Swertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo Study
Transplanting islets serves best option for restoring lost beta cell mass and function. Small bio-chemical agents do have the potential to generate new islets mass, however lack of understanding about mechanistic action of these small molecules eventually restricts their use in cell-based therapies...
Autores principales: | Dadheech, Nidheesh, Srivastava, Abhay, Paranjape, Neha, Gupta, Shivika, Dave, Arpita, Shah, Girish M., Bhonde, Ramesh R., Gupta, Sarita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457488/ https://www.ncbi.nlm.nih.gov/pubmed/26047129 http://dx.doi.org/10.1371/journal.pone.0128244 |
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