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Synthetic Long Peptide Influenza Vaccine Containing Conserved T and B Cell Epitopes Reduces Viral Load in Lungs of Mice and Ferrets

Currently licensed influenza vaccines mainly induce antibodies against highly variable epitopes. Due to antigenic drift, protection is subtype or strain-specific and regular vaccine updates are required. In case of antigenic shifts, which have caused several pandemics in the past, completely new vac...

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Detalles Bibliográficos
Autores principales: Rosendahl Huber, S. K., Camps, M. G. M., Jacobi, R. H. J., Mouthaan, J., van Dijken, H., van Beek, J., Ossendorp, F., de Jonge, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457525/
https://www.ncbi.nlm.nih.gov/pubmed/26046664
http://dx.doi.org/10.1371/journal.pone.0127969