Evidence that MHC I-E dampens thyroid autoantibodies and prevents spreading to a second thyroid autoantigen in I-A(k) NOD mice

NOD.H2(k) and NOD.H2(h4) mice carry the MHC class II molecule I-A(k) associated with susceptibility to experimentally-induced thyroiditis. Dietary iodine enhanced spontaneous thyroid autoimmunity, well known in NOD.H2(h4) mice, has not been investigated in NOD.H2(k) mice. We compared NOD.H2(h4) and...

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Detalles Bibliográficos
Autores principales: Pelletier, Adam-Nicolas, Aliesky, Holly A., Banuelos, Bianca, Chabot-Roy, Geneviève, Rapoport, Basil, Lesage, Sylvie, McLachlan, Sandra M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457582/
https://www.ncbi.nlm.nih.gov/pubmed/25811933
http://dx.doi.org/10.1038/gene.2015.7

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