Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions

Most cases of congenital obstructive nephropathy are the result of ureteropelvic junction obstructions, and despite their high prevalence, we have a poor understanding of their etiology and scarcity of genetic models. The eight-protein exocyst complex regulates polarized exocytosis of intracellular...

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Detalles Bibliográficos
Autores principales: Fogelgren, Ben, Polgar, Noemi, Lui, Vanessa H., Lee, Amanda J., Tamashiro, Kadee-Kalia A., Napoli, Josephine Andrea, Walton, Chad B., Zuo, Xiaofeng, Lipschutz, Joshua H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457632/
https://www.ncbi.nlm.nih.gov/pubmed/26046524
http://dx.doi.org/10.1371/journal.pone.0129346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457632/
https://www.ncbi.nlm.nih.gov/pubmed/26046524
http://dx.doi.org/10.1371/journal.pone.0129346

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