Cargando…

Release of Phosphorylated HSP27 (HSPB1) from Platelets Is Accompanied with the Acceleration of Aggregation in Diabetic Patients

We investigated the relationship between HSP27 phosphorylation and collagen-stimulated activation of platelets in patients with diabetes mellitus (DM). Platelet-rich plasma was prepared from blood of type 2 DM patients. The platelet aggregation was analyzed in size of aggregates by an aggregometer u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tokuda, Haruhiko, Kuroyanagi, Gen, Tsujimoto, Masanori, Enomoto, Yukiko, Matsushima-Nishiwaki, Rie, Onuma, Takashi, Kojima, Akiko, Doi, Tomoaki, Tanabe, Kumiko, Akamatsu, Shigeru, Iida, Hiroki, Ogura, Shinji, Otsuka, Takanobu, Iwama, Toru, Tanikawa, Takahisa, Ishikawa, Kei, Kojima, Kumi, Kozawa, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457785/ https://www.ncbi.nlm.nih.gov/pubmed/26046355 http://dx.doi.org/10.1371/journal.pone.0128977

Ejemplares similares

Thrombin Receptor-Activating Protein (TRAP)-Activated Akt Is Involved in the Release of Phosphorylated-HSP27 (HSPB1) from Platelets in DM Patients
por: Tokuda, Haruhiko, et al.
Publicado: (2016)

Factor Xa Inhibitor Suppresses the Release of Phosphorylated HSP27 from Collagen-Stimulated Human Platelets: Inhibition of HSP27 Phosphorylation via p44/p42 MAP Kinase
por: Tsujimoto, Masanori, et al.
Publicado: (2016)

Heat shock protein 27 (HSPB1) suppresses the PDGF-BB-induced migration of osteoblasts
por: Kainuma, Shingo, et al.
Publicado: (2017)

HSP22 (HSPB8) positively regulates PGF2α-induced synthesis of interleukin-6 and vascular endothelial growth factor in osteoblasts
por: Kuroyanagi, Gen, et al.
Publicado: (2021)

Synergistic effect of collagen and CXCL12 in the low doses on human platelet activation
por: Nakashima, Daiki, et al.
Publicado: (2020)

Synergy by Ristocetin and CXCL12 in Human Platelet Activation: Divergent Regulation by Rho/Rho-Kinase and Rac
por: Enomoto, Yukiko, et al.
Publicado: (2023)

Thrombopoietin and collagen in low doses cooperatively induce human platelet activation
por: Doi, Tomoaki, et al.
Publicado: (2022)

Cigarette Smoking Cessation Temporarily Enhances the Release of Phosphorylated-HSP27 from Human Platelets
por: Onuma, Takashi, et al.
Publicado: (2020)

Relationship between the Responsiveness of Amyloid β Protein to Platelet Activation by TRAP Stimulation and Brain Atrophy in Patients with Diabetes Mellitus
por: Hori, Takamitsu, et al.
Publicado: (2022)

HSP70 inhibitors upregulate prostaglandin E(1)-induced synthesis of interleukin-6 in osteoblasts
por: Kuroyanagi, Gen, et al.
Publicado: (2022)

Smoking cessation affects human platelet activation induced by collagen
por: Kito, Yuko, et al.
Publicado: (2019)

Down-Regulation by Resveratrol of Basic Fibroblast Growth Factor-Stimulated Osteoprotegerin Synthesis through Suppression of Akt in Osteoblasts
por: Kuroyanagi, Gen, et al.
Publicado: (2014)

HSP70 Inhibitor Suppresses IGF-I-Stimulated Migration of Osteoblasts through p44/p42 MAP Kinase
por: Kawabata, Tetsu, et al.
Publicado: (2018)

Tramadol regulates the activation of human platelets via Rac but not Rho/Rho-kinase
por: Iida, Hiroki, et al.
Publicado: (2023)

Tramadol enhances PGF(2α)-stimulated osteoprotegerin synthesis in osteoblasts
por: Kim, Woo, et al.
Publicado: (2020)

Upregulation of TGF-β-induced HSP27 by HSP90 inhibitors in osteoblasts
por: Kuroyanagi, Gen, et al.
Publicado: (2022)

HSP90 inhibitors potentiate PGF(2α)-induced IL-6 synthesis via p38 MAP kinase in osteoblasts
por: Fujita, Kazuhiko, et al.
Publicado: (2017)

(−)-Epigallocatechin gallate but not chlorogenic acid suppresses EGF-stimulated migration of osteoblasts via attenuation of p38 MAPK activity
por: Kawabata, Tetsu, et al.
Publicado: (2018)

Incretin accelerates platelet-derived growth factor-BB-induced osteoblast migration via protein kinase A: The upregulation of p38 MAP kinase
por: Kawabata, Tetsu, et al.
Publicado: (2020)

Involvement of AMP-activated protein kinase in TGF-β-stimulated VEGF synthesis in osteoblasts
por: MIZUTANI, JUN, et al.
Publicado: (2012)

(-)-Epigallocatechin Gallate Reduces Platelet-Derived Growth Factor-BB-Stimulated Interleukin-6 Synthesis in Osteoblasts: Suppression of SAPK/JNK
por: Takai, Shinji, et al.
Publicado: (2008)

Leg lymphedema caused by iliopectineal bursitis associated with destruction of a rheumatoid hip joint: A case report
por: KUROYANAGI, GEN, et al.
Publicado: (2013)

Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells
por: Tanabe, Kumiko, et al.
Publicado: (2010)

Phosphorylated Heat Shock Protein 20 (HSPB6) Regulates Transforming Growth Factor-α-Induced Migration and Invasion of Hepatocellular Carcinoma Cells
por: Matsushima-Nishiwaki, Rie, et al.
Publicado: (2016)

Direct Association of Heat Shock Protein 20 (HSPB6) with Phosphoinositide 3-kinase (PI3K) in Human Hepatocellular Carcinoma: Regulation of the PI3K Activity
por: Matsushima-Nishiwaki, Rie, et al.
Publicado: (2013)

Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells
por: Tanabe, Kumiko, et al.
Publicado: (2011)

HSPB1, HSPB6, HSPB7 and HSPB8 Protect against RhoA GTPase-Induced Remodeling in Tachypaced Atrial Myocytes
por: Ke, Lei, et al.
Publicado: (2011)

Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution
por: Benndorf, Rainer, et al.
Publicado: (2022)

The Clinical Significance of Phosphorylated Heat Shock Protein 27 (HSPB1) in Pancreatic Cancer
por: Okuno, Mitsuru, et al.
Publicado: (2016)

The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8
por: Shatov, Vladislav M., et al.
Publicado: (2018)

HspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins
por: Arrigo, André-Patrick, et al.
Publicado: (2014)

Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation
por: LIN, JIAYING, et al.
Publicado: (2014)

Characterization of Hspb8 in Zebrafish
por: Dubińska-Magiera, Magda, et al.
Publicado: (2020)

Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2
por: Matsushima-Nishiwaki, Rie, et al.
Publicado: (2018)

Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3
por: Clark, Alice R., et al.
Publicado: (2018)

Edaravone attenuates sustained pial arteriolar vasoconstriction independently of endothelial function after unclamping of the abdominal aorta in rabbits
por: Michino, Tomohiro, et al.
Publicado: (2021)

Leiomyoma treatment by uterine artery embolization using gelatin sponge prepared by the pumping method
por: KOJIMA, TAKAHISA, et al.
Publicado: (2012)

Phosphoserine-86-HSPB1 (pS86-HSPB1) is cytoplasmic and highly induced in rat myometrium at labour
por: Miskiewicz, E. I., et al.
Publicado: (2022)

Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners
por: Hussein, Rasha M., et al.
Publicado: (2015)

Bmal1 Regulates the Redox Rhythm of HSPB1, and Homooxidized HSPB1 Attenuates the Oxidative Stress Injury of Cardiomyocytes
por: Liu, Xiehong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nc02qm2fu9m9foetinfrj65k7f