Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans

Studies of CO ligand binding revealed that two protein states with different ligand affinities exist in the protoglobin from Methanosarcina acetivorans (in MaPgb*, residue Cys(E20)101 was mutated to Ser). The switch between the two states occurs upon the ligation of MaPgb*. In this work, site-direct...

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Detalles Bibliográficos
Autores principales: Tilleman, Lesley, Abbruzzetti, Stefania, Ciaccio, Chiara, De Sanctis, Giampiero, Nardini, Marco, Pesce, Alessandra, Desmet, Filip, Moens, Luc, Van Doorslaer, Sabine, Bruno, Stefano, Bolognesi, Martino, Ascenzi, Paolo, Coletta, Massimo, Viappiani, Cristiano, Dewilde, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457829/
https://www.ncbi.nlm.nih.gov/pubmed/26047471
http://dx.doi.org/10.1371/journal.pone.0125959

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