Cargando…
Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver
Ablation of glycosylated lysosomal membrane protein (GLMP, formerly known as NCU-G1) has been shown to cause chronic liver injury which progresses into liver fibrosis in mice. Both lysosomal dysfunction and chronic liver injury can cause metabolic dysregulation. Glmp(gt/gt) mice (formerly known as N...
Autores principales: | Kong, Xiang Yi, Kase, Eili Tranheim, Herskedal, Anette, Schjalm, Camilla, Damme, Markus, Nesset, Cecilie Kasi, Thoresen, G. Hege, Rustan, Arild C., Eskild, Winnie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457871/ https://www.ncbi.nlm.nih.gov/pubmed/26047317 http://dx.doi.org/10.1371/journal.pone.0129402 |
Ejemplares similares
-
Age-dependent development of liver fibrosis in Glmp(gt/gt) mice
por: Nesset, Cecilie K., et al.
Publicado: (2016) -
Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells
por: Kong, Xiang Y., et al.
Publicado: (2014) -
Development of three-dimensional primary human myospheres as culture model of skeletal muscle cells for metabolic studies
por: Dalmao-Fernandez, Andrea, et al.
Publicado: (2023) -
The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP
por: Massa López, David, et al.
Publicado: (2019) -
Remodeling of Oxidative Energy Metabolism by Galactose Improves Glucose Handling and Metabolic Switching in Human Skeletal Muscle Cells
por: Kase, Eili Tranheim, et al.
Publicado: (2013)