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Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver

Ablation of glycosylated lysosomal membrane protein (GLMP, formerly known as NCU-G1) has been shown to cause chronic liver injury which progresses into liver fibrosis in mice. Both lysosomal dysfunction and chronic liver injury can cause metabolic dysregulation. Glmp(gt/gt) mice (formerly known as N...

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Detalles Bibliográficos
Autores principales: Kong, Xiang Yi, Kase, Eili Tranheim, Herskedal, Anette, Schjalm, Camilla, Damme, Markus, Nesset, Cecilie Kasi, Thoresen, G. Hege, Rustan, Arild C., Eskild, Winnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457871/
https://www.ncbi.nlm.nih.gov/pubmed/26047317
http://dx.doi.org/10.1371/journal.pone.0129402

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