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Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination

The recombination activity of Escherichia coli (E. coli) RecA protein reflects an evolutionary balance between the positive and potentially deleterious effects of recombination. We have perturbed that balance, generating RecA variants exhibiting improved recombination functionality via random mutage...

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Detalles Bibliográficos
Autores principales:	Kim, Taejin, Chitteni-Pattu, Sindhu, Cox, Benjamin L., Wood, Elizabeth A., Sandler, Steven J., Cox, Michael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457935/ https://www.ncbi.nlm.nih.gov/pubmed/26047498 http://dx.doi.org/10.1371/journal.pgen.1005278

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