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Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis

Tenosynovial giant cell tumour, diffuse type, also known under a variety of other terms including diffuse pigmented villonodular synovitis, tends to be locally aggressive and not infrequently can show multiple recurrences. The differential diagnosis with the extremely rare and somewhat controversial...

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Autores principales: Righi, A, Gambarotti, M, Sbaraglia, M, Frisoni, T, Donati, D, Vanel, D, Dei Tos, A P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458002/
https://www.ncbi.nlm.nih.gov/pubmed/26052431
http://dx.doi.org/10.1186/s13569-015-0030-2
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author Righi, A
Gambarotti, M
Sbaraglia, M
Frisoni, T
Donati, D
Vanel, D
Dei Tos, A P
author_facet Righi, A
Gambarotti, M
Sbaraglia, M
Frisoni, T
Donati, D
Vanel, D
Dei Tos, A P
author_sort Righi, A
collection PubMed
description Tenosynovial giant cell tumour, diffuse type, also known under a variety of other terms including diffuse pigmented villonodular synovitis, tends to be locally aggressive and not infrequently can show multiple recurrences. The differential diagnosis with the extremely rare and somewhat controversial malignant variant of tenosynovial giant cell tumour, diffuse type, is challenging due to overlapping radiologic features of these two entities. Malignant tenosynovial giant cell tumour is defined by the presence of overtly malignant sarcomatous areas. We describe a very unusual case of a 63-year-old man affected by tenosynovial giant cell tumour, diffuse type of the knee that, despite absence of morphologic evidence of sarcomatous transformation, developed inguinal lymph node metastases following multiple surgical procedures.
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spelling pubmed-44580022015-06-07 Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis Righi, A Gambarotti, M Sbaraglia, M Frisoni, T Donati, D Vanel, D Dei Tos, A P Clin Sarcoma Res Case Report Tenosynovial giant cell tumour, diffuse type, also known under a variety of other terms including diffuse pigmented villonodular synovitis, tends to be locally aggressive and not infrequently can show multiple recurrences. The differential diagnosis with the extremely rare and somewhat controversial malignant variant of tenosynovial giant cell tumour, diffuse type, is challenging due to overlapping radiologic features of these two entities. Malignant tenosynovial giant cell tumour is defined by the presence of overtly malignant sarcomatous areas. We describe a very unusual case of a 63-year-old man affected by tenosynovial giant cell tumour, diffuse type of the knee that, despite absence of morphologic evidence of sarcomatous transformation, developed inguinal lymph node metastases following multiple surgical procedures. BioMed Central 2015-06-06 /pmc/articles/PMC4458002/ /pubmed/26052431 http://dx.doi.org/10.1186/s13569-015-0030-2 Text en © Righi et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Righi, A
Gambarotti, M
Sbaraglia, M
Frisoni, T
Donati, D
Vanel, D
Dei Tos, A P
Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis
title Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis
title_full Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis
title_fullStr Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis
title_full_unstemmed Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis
title_short Metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis
title_sort metastasizing tenosynovial giant cell tumour, diffuse type/pigmented villonodular synovitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458002/
https://www.ncbi.nlm.nih.gov/pubmed/26052431
http://dx.doi.org/10.1186/s13569-015-0030-2
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