Longitudinal analysis of peripheral blood T cell receptor diversity in patients with systemic lupus erythematosus by next-generation sequencing

INTRODUCTION: T cells play an important role in the pathogenesis of systemic lupus erythematosus (SLE). Clonal expansion of T cells correlating with disease activity has been observed in peripheral blood (PB) of SLE subjects. Recently, next-generation sequencing (NGS) of the T cell receptor (TCR) β...

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Detalles Bibliográficos
Autores principales: Thapa, Dharma R, Tonikian, Raffi, Sun, Chao, Liu, Mei, Dearth, Andrea, Petri, Michelle, Pepin, Francois, Emerson, Ryan O, Ranger, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458014/
https://www.ncbi.nlm.nih.gov/pubmed/26001779
http://dx.doi.org/10.1186/s13075-015-0655-9

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