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APC selectively mediates response to chemotherapeutic agents in breast cancer

BACKGROUND: The Adenomatous Polyposis Coli (APC) tumor suppressor is mutated or hypermethylated in up to 70 % of sporadic breast cancers depending on subtype; however, the effects of APC mutation on tumorigenic properties remain unexplored. Using the Apc(Min/+) mouse crossed to the Polyoma middle T...

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Detalles Bibliográficos
Autores principales:	VanKlompenberg, Monica K., Bedalov, Claire O., Soto, Katia Fernandez, Prosperi, Jenifer R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458029/ https://www.ncbi.nlm.nih.gov/pubmed/26049416 http://dx.doi.org/10.1186/s12885-015-1456-x

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