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A four-year cardiovascular risk score for type 2 diabetic inpatients

As cardiovascular risk tables currently in use were constructed using data from the general population, the cardiovascular risk of patients admitted via the hospital emergency department may be underestimated. Accordingly, we constructed a predictive model for the appearance of cardiovascular diseas...

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Autores principales: Ramírez-Prado, Dolores, Palazón-Bru, Antonio, Folgado-de la Rosa, David Manuel, Carbonell-Torregrosa, María Ángeles, Martínez-Díaz, Ana María, Martínez-St. John, Damian Robert James, Gil-Guillén, Vicente Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458124/
https://www.ncbi.nlm.nih.gov/pubmed/26056618
http://dx.doi.org/10.7717/peerj.984
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author Ramírez-Prado, Dolores
Palazón-Bru, Antonio
Folgado-de la Rosa, David Manuel
Carbonell-Torregrosa, María Ángeles
Martínez-Díaz, Ana María
Martínez-St. John, Damian Robert James
Gil-Guillén, Vicente Francisco
author_facet Ramírez-Prado, Dolores
Palazón-Bru, Antonio
Folgado-de la Rosa, David Manuel
Carbonell-Torregrosa, María Ángeles
Martínez-Díaz, Ana María
Martínez-St. John, Damian Robert James
Gil-Guillén, Vicente Francisco
author_sort Ramírez-Prado, Dolores
collection PubMed
description As cardiovascular risk tables currently in use were constructed using data from the general population, the cardiovascular risk of patients admitted via the hospital emergency department may be underestimated. Accordingly, we constructed a predictive model for the appearance of cardiovascular diseases in patients with type 2 diabetes admitted via the emergency department. We undertook a four-year follow-up of a cohort of 112 adult patients with type 2 diabetes admitted via the emergency department for any cause except patients admitted with acute myocardial infarction, stroke, cancer, or a palliative status. The sample was selected randomly between 2010 and 2012. The primary outcome was time to cardiovascular disease. Other variables (at baseline) were gender, age, heart failure, renal failure, depression, asthma/chronic obstructive pulmonary disease, hypertension, dyslipidaemia, insulin, smoking, admission for cardiovascular causes, pills per day, walking habit, fasting blood glucose and creatinine. A cardiovascular risk table was constructed based on the score to estimate the likelihood of cardiovascular disease. Risk groups were established and the c-statistic was calculated. Over a mean follow-up of 2.31 years, 39 patients had cardiovascular disease (34.8%, 95% CI [26.0–43.6%]). Predictive factors were gender, age, hypertension, renal failure, insulin, admission due to cardiovascular reasons and walking habit. The c-statistic was 0.734 (standard error: 0.049). After validation, this study will provide a tool for the primary health care services to enable the short-term prediction of cardiovascular disease after hospital discharge in patients with type 2 diabetes admitted via the emergency department.
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spelling pubmed-44581242015-06-08 A four-year cardiovascular risk score for type 2 diabetic inpatients Ramírez-Prado, Dolores Palazón-Bru, Antonio Folgado-de la Rosa, David Manuel Carbonell-Torregrosa, María Ángeles Martínez-Díaz, Ana María Martínez-St. John, Damian Robert James Gil-Guillén, Vicente Francisco PeerJ Diabetes and Endocrinology As cardiovascular risk tables currently in use were constructed using data from the general population, the cardiovascular risk of patients admitted via the hospital emergency department may be underestimated. Accordingly, we constructed a predictive model for the appearance of cardiovascular diseases in patients with type 2 diabetes admitted via the emergency department. We undertook a four-year follow-up of a cohort of 112 adult patients with type 2 diabetes admitted via the emergency department for any cause except patients admitted with acute myocardial infarction, stroke, cancer, or a palliative status. The sample was selected randomly between 2010 and 2012. The primary outcome was time to cardiovascular disease. Other variables (at baseline) were gender, age, heart failure, renal failure, depression, asthma/chronic obstructive pulmonary disease, hypertension, dyslipidaemia, insulin, smoking, admission for cardiovascular causes, pills per day, walking habit, fasting blood glucose and creatinine. A cardiovascular risk table was constructed based on the score to estimate the likelihood of cardiovascular disease. Risk groups were established and the c-statistic was calculated. Over a mean follow-up of 2.31 years, 39 patients had cardiovascular disease (34.8%, 95% CI [26.0–43.6%]). Predictive factors were gender, age, hypertension, renal failure, insulin, admission due to cardiovascular reasons and walking habit. The c-statistic was 0.734 (standard error: 0.049). After validation, this study will provide a tool for the primary health care services to enable the short-term prediction of cardiovascular disease after hospital discharge in patients with type 2 diabetes admitted via the emergency department. PeerJ Inc. 2015-06-02 /pmc/articles/PMC4458124/ /pubmed/26056618 http://dx.doi.org/10.7717/peerj.984 Text en © 2015 Ramírez-Prado et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Diabetes and Endocrinology
Ramírez-Prado, Dolores
Palazón-Bru, Antonio
Folgado-de la Rosa, David Manuel
Carbonell-Torregrosa, María Ángeles
Martínez-Díaz, Ana María
Martínez-St. John, Damian Robert James
Gil-Guillén, Vicente Francisco
A four-year cardiovascular risk score for type 2 diabetic inpatients
title A four-year cardiovascular risk score for type 2 diabetic inpatients
title_full A four-year cardiovascular risk score for type 2 diabetic inpatients
title_fullStr A four-year cardiovascular risk score for type 2 diabetic inpatients
title_full_unstemmed A four-year cardiovascular risk score for type 2 diabetic inpatients
title_short A four-year cardiovascular risk score for type 2 diabetic inpatients
title_sort four-year cardiovascular risk score for type 2 diabetic inpatients
topic Diabetes and Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458124/
https://www.ncbi.nlm.nih.gov/pubmed/26056618
http://dx.doi.org/10.7717/peerj.984
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