Cargando…
A four-year cardiovascular risk score for type 2 diabetic inpatients
As cardiovascular risk tables currently in use were constructed using data from the general population, the cardiovascular risk of patients admitted via the hospital emergency department may be underestimated. Accordingly, we constructed a predictive model for the appearance of cardiovascular diseas...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458124/ https://www.ncbi.nlm.nih.gov/pubmed/26056618 http://dx.doi.org/10.7717/peerj.984 |
_version_ | 1782375055980756992 |
---|---|
author | Ramírez-Prado, Dolores Palazón-Bru, Antonio Folgado-de la Rosa, David Manuel Carbonell-Torregrosa, María Ángeles Martínez-Díaz, Ana María Martínez-St. John, Damian Robert James Gil-Guillén, Vicente Francisco |
author_facet | Ramírez-Prado, Dolores Palazón-Bru, Antonio Folgado-de la Rosa, David Manuel Carbonell-Torregrosa, María Ángeles Martínez-Díaz, Ana María Martínez-St. John, Damian Robert James Gil-Guillén, Vicente Francisco |
author_sort | Ramírez-Prado, Dolores |
collection | PubMed |
description | As cardiovascular risk tables currently in use were constructed using data from the general population, the cardiovascular risk of patients admitted via the hospital emergency department may be underestimated. Accordingly, we constructed a predictive model for the appearance of cardiovascular diseases in patients with type 2 diabetes admitted via the emergency department. We undertook a four-year follow-up of a cohort of 112 adult patients with type 2 diabetes admitted via the emergency department for any cause except patients admitted with acute myocardial infarction, stroke, cancer, or a palliative status. The sample was selected randomly between 2010 and 2012. The primary outcome was time to cardiovascular disease. Other variables (at baseline) were gender, age, heart failure, renal failure, depression, asthma/chronic obstructive pulmonary disease, hypertension, dyslipidaemia, insulin, smoking, admission for cardiovascular causes, pills per day, walking habit, fasting blood glucose and creatinine. A cardiovascular risk table was constructed based on the score to estimate the likelihood of cardiovascular disease. Risk groups were established and the c-statistic was calculated. Over a mean follow-up of 2.31 years, 39 patients had cardiovascular disease (34.8%, 95% CI [26.0–43.6%]). Predictive factors were gender, age, hypertension, renal failure, insulin, admission due to cardiovascular reasons and walking habit. The c-statistic was 0.734 (standard error: 0.049). After validation, this study will provide a tool for the primary health care services to enable the short-term prediction of cardiovascular disease after hospital discharge in patients with type 2 diabetes admitted via the emergency department. |
format | Online Article Text |
id | pubmed-4458124 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | PeerJ Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-44581242015-06-08 A four-year cardiovascular risk score for type 2 diabetic inpatients Ramírez-Prado, Dolores Palazón-Bru, Antonio Folgado-de la Rosa, David Manuel Carbonell-Torregrosa, María Ángeles Martínez-Díaz, Ana María Martínez-St. John, Damian Robert James Gil-Guillén, Vicente Francisco PeerJ Diabetes and Endocrinology As cardiovascular risk tables currently in use were constructed using data from the general population, the cardiovascular risk of patients admitted via the hospital emergency department may be underestimated. Accordingly, we constructed a predictive model for the appearance of cardiovascular diseases in patients with type 2 diabetes admitted via the emergency department. We undertook a four-year follow-up of a cohort of 112 adult patients with type 2 diabetes admitted via the emergency department for any cause except patients admitted with acute myocardial infarction, stroke, cancer, or a palliative status. The sample was selected randomly between 2010 and 2012. The primary outcome was time to cardiovascular disease. Other variables (at baseline) were gender, age, heart failure, renal failure, depression, asthma/chronic obstructive pulmonary disease, hypertension, dyslipidaemia, insulin, smoking, admission for cardiovascular causes, pills per day, walking habit, fasting blood glucose and creatinine. A cardiovascular risk table was constructed based on the score to estimate the likelihood of cardiovascular disease. Risk groups were established and the c-statistic was calculated. Over a mean follow-up of 2.31 years, 39 patients had cardiovascular disease (34.8%, 95% CI [26.0–43.6%]). Predictive factors were gender, age, hypertension, renal failure, insulin, admission due to cardiovascular reasons and walking habit. The c-statistic was 0.734 (standard error: 0.049). After validation, this study will provide a tool for the primary health care services to enable the short-term prediction of cardiovascular disease after hospital discharge in patients with type 2 diabetes admitted via the emergency department. PeerJ Inc. 2015-06-02 /pmc/articles/PMC4458124/ /pubmed/26056618 http://dx.doi.org/10.7717/peerj.984 Text en © 2015 Ramírez-Prado et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. |
spellingShingle | Diabetes and Endocrinology Ramírez-Prado, Dolores Palazón-Bru, Antonio Folgado-de la Rosa, David Manuel Carbonell-Torregrosa, María Ángeles Martínez-Díaz, Ana María Martínez-St. John, Damian Robert James Gil-Guillén, Vicente Francisco A four-year cardiovascular risk score for type 2 diabetic inpatients |
title | A four-year cardiovascular risk score for type 2 diabetic inpatients |
title_full | A four-year cardiovascular risk score for type 2 diabetic inpatients |
title_fullStr | A four-year cardiovascular risk score for type 2 diabetic inpatients |
title_full_unstemmed | A four-year cardiovascular risk score for type 2 diabetic inpatients |
title_short | A four-year cardiovascular risk score for type 2 diabetic inpatients |
title_sort | four-year cardiovascular risk score for type 2 diabetic inpatients |
topic | Diabetes and Endocrinology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458124/ https://www.ncbi.nlm.nih.gov/pubmed/26056618 http://dx.doi.org/10.7717/peerj.984 |
work_keys_str_mv | AT ramirezpradodolores afouryearcardiovascularriskscorefortype2diabeticinpatients AT palazonbruantonio afouryearcardiovascularriskscorefortype2diabeticinpatients AT folgadodelarosadavidmanuel afouryearcardiovascularriskscorefortype2diabeticinpatients AT carbonelltorregrosamariaangeles afouryearcardiovascularriskscorefortype2diabeticinpatients AT martinezdiazanamaria afouryearcardiovascularriskscorefortype2diabeticinpatients AT martinezstjohndamianrobertjames afouryearcardiovascularriskscorefortype2diabeticinpatients AT gilguillenvicentefrancisco afouryearcardiovascularriskscorefortype2diabeticinpatients AT ramirezpradodolores fouryearcardiovascularriskscorefortype2diabeticinpatients AT palazonbruantonio fouryearcardiovascularriskscorefortype2diabeticinpatients AT folgadodelarosadavidmanuel fouryearcardiovascularriskscorefortype2diabeticinpatients AT carbonelltorregrosamariaangeles fouryearcardiovascularriskscorefortype2diabeticinpatients AT martinezdiazanamaria fouryearcardiovascularriskscorefortype2diabeticinpatients AT martinezstjohndamianrobertjames fouryearcardiovascularriskscorefortype2diabeticinpatients AT gilguillenvicentefrancisco fouryearcardiovascularriskscorefortype2diabeticinpatients |