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Selected maternal morbidities in women with a prior caesarean delivery planning vaginal birth or elective repeat caesarean section: a retrospective cohort analysis using data from the UK Obstetric Surveillance System

OBJECTIVE: To conduct a secondary analysis of data from the UK Obstetric Surveillance System (UKOSS) to estimate the rates of specific maternal risks associated with planned vaginal birth after caesarean (VBAC) and elective repeat caesarean section (ERCS). DESIGN: A retrospective cohort analysis usi...

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Autores principales: Nair, Manisha, Soffer, Kate, Noor, Nudrat, Knight, Marian, Griffiths, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458629/
https://www.ncbi.nlm.nih.gov/pubmed/26038358
http://dx.doi.org/10.1136/bmjopen-2014-007434
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author Nair, Manisha
Soffer, Kate
Noor, Nudrat
Knight, Marian
Griffiths, Malcolm
author_facet Nair, Manisha
Soffer, Kate
Noor, Nudrat
Knight, Marian
Griffiths, Malcolm
author_sort Nair, Manisha
collection PubMed
description OBJECTIVE: To conduct a secondary analysis of data from the UK Obstetric Surveillance System (UKOSS) to estimate the rates of specific maternal risks associated with planned vaginal birth after caesarean (VBAC) and elective repeat caesarean section (ERCS). DESIGN: A retrospective cohort analysis using UKOSS data from 4 studies conducted between 2005 and 2012. SETTING: All hospitals with consultant-led maternity units in the UK. POPULATION: Pregnant women who had a previous caesarean section. METHOD: Women who had undergone a previous caesarean section were divided into 2 exposure groups: planned VBAC and ERCS. We calculated the incidence of each of the 4 outcomes of interest with 95% CIs for the 2 exposure groups using proxy denominators (total estimated VBAC and ERCS maternities in a given year). Incidences were compared between groups using χ(2) test or Fisher's exact test and risk ratios with 95% CI. MAIN OUTCOME MEASURES: Severe maternal morbidities: peripartum hysterectomy, severe sepsis, peripartum haemorrhage and failed tracheal intubation. RESULTS: The risks of all complications examined in both groups were low. The rates of peripartum hysterectomy, severe sepsis, peripartum haemorrhage and failed tracheal intubation were not significantly different between the 2 groups in absolute or relative terms. CONCLUSIONS: While the risk of uterine rupture in the VBAC and ERCS groups is well understood, this national study did not demonstrate any other clear differences in the outcomes we examined. The absolute and relative risks of maternal complications were small in both groups. Large epidemiological studies could further help to assess whether the incidence of these rare outcomes would significantly differ between the VBAC and ERCS groups if a larger number of cases were to be examined. In the interim, this study provides important information to help pregnant women in their decision-making process.
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spelling pubmed-44586292015-06-10 Selected maternal morbidities in women with a prior caesarean delivery planning vaginal birth or elective repeat caesarean section: a retrospective cohort analysis using data from the UK Obstetric Surveillance System Nair, Manisha Soffer, Kate Noor, Nudrat Knight, Marian Griffiths, Malcolm BMJ Open Obstetrics and Gynaecology OBJECTIVE: To conduct a secondary analysis of data from the UK Obstetric Surveillance System (UKOSS) to estimate the rates of specific maternal risks associated with planned vaginal birth after caesarean (VBAC) and elective repeat caesarean section (ERCS). DESIGN: A retrospective cohort analysis using UKOSS data from 4 studies conducted between 2005 and 2012. SETTING: All hospitals with consultant-led maternity units in the UK. POPULATION: Pregnant women who had a previous caesarean section. METHOD: Women who had undergone a previous caesarean section were divided into 2 exposure groups: planned VBAC and ERCS. We calculated the incidence of each of the 4 outcomes of interest with 95% CIs for the 2 exposure groups using proxy denominators (total estimated VBAC and ERCS maternities in a given year). Incidences were compared between groups using χ(2) test or Fisher's exact test and risk ratios with 95% CI. MAIN OUTCOME MEASURES: Severe maternal morbidities: peripartum hysterectomy, severe sepsis, peripartum haemorrhage and failed tracheal intubation. RESULTS: The risks of all complications examined in both groups were low. The rates of peripartum hysterectomy, severe sepsis, peripartum haemorrhage and failed tracheal intubation were not significantly different between the 2 groups in absolute or relative terms. CONCLUSIONS: While the risk of uterine rupture in the VBAC and ERCS groups is well understood, this national study did not demonstrate any other clear differences in the outcomes we examined. The absolute and relative risks of maternal complications were small in both groups. Large epidemiological studies could further help to assess whether the incidence of these rare outcomes would significantly differ between the VBAC and ERCS groups if a larger number of cases were to be examined. In the interim, this study provides important information to help pregnant women in their decision-making process. BMJ Publishing Group 2015-06-02 /pmc/articles/PMC4458629/ /pubmed/26038358 http://dx.doi.org/10.1136/bmjopen-2014-007434 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
spellingShingle Obstetrics and Gynaecology
Nair, Manisha
Soffer, Kate
Noor, Nudrat
Knight, Marian
Griffiths, Malcolm
Selected maternal morbidities in women with a prior caesarean delivery planning vaginal birth or elective repeat caesarean section: a retrospective cohort analysis using data from the UK Obstetric Surveillance System
title Selected maternal morbidities in women with a prior caesarean delivery planning vaginal birth or elective repeat caesarean section: a retrospective cohort analysis using data from the UK Obstetric Surveillance System
title_full Selected maternal morbidities in women with a prior caesarean delivery planning vaginal birth or elective repeat caesarean section: a retrospective cohort analysis using data from the UK Obstetric Surveillance System
title_fullStr Selected maternal morbidities in women with a prior caesarean delivery planning vaginal birth or elective repeat caesarean section: a retrospective cohort analysis using data from the UK Obstetric Surveillance System
title_full_unstemmed Selected maternal morbidities in women with a prior caesarean delivery planning vaginal birth or elective repeat caesarean section: a retrospective cohort analysis using data from the UK Obstetric Surveillance System
title_short Selected maternal morbidities in women with a prior caesarean delivery planning vaginal birth or elective repeat caesarean section: a retrospective cohort analysis using data from the UK Obstetric Surveillance System
title_sort selected maternal morbidities in women with a prior caesarean delivery planning vaginal birth or elective repeat caesarean section: a retrospective cohort analysis using data from the uk obstetric surveillance system
topic Obstetrics and Gynaecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458629/
https://www.ncbi.nlm.nih.gov/pubmed/26038358
http://dx.doi.org/10.1136/bmjopen-2014-007434
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