Mitochondrial E3 ligase March5 maintains stemness of mouse ES cells via suppression of ERK signalling

Embryonic stem cells (ESCs) possess pluripotency, which is the capacity of cells to differentiate into all lineages of the mature organism. Increasing evidence suggests that the pluripotent state of ESCs is regulated by a combination of extrinsic and intrinsic factors. The underlying mechanisms, how...

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Detalles Bibliográficos
Autores principales: Gu, Hao, Li, Qidong, Huang, Shan, Lu, Weiguang, Cheng, Fangyuan, Gao, Ping, Wang, Chen, Miao, Lin, Mei, Yide, Wu, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458872/
https://www.ncbi.nlm.nih.gov/pubmed/26033541
http://dx.doi.org/10.1038/ncomms8112

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