Developmental-stage-dependent transcriptional response to leukaemic oncogene expression

Acute myeloid leukaemia (AML) is characterized by a block in myeloid differentiation the stage of which is dependent on the nature of the transforming oncogene and the developmental stage of the oncogenic hit. This is also true for the t(8;21) translocation that gives rise to the RUNX1-ETO fusion pr...

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Detalles Bibliográficos
Autores principales: Regha, Kakkad, Assi, Salam A., Tsoulaki, Olga, Gilmour, Jane, Lacaud, Georges, Bonifer, Constanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458875/
https://www.ncbi.nlm.nih.gov/pubmed/26018585
http://dx.doi.org/10.1038/ncomms8203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458875/
https://www.ncbi.nlm.nih.gov/pubmed/26018585
http://dx.doi.org/10.1038/ncomms8203

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