Platelet actin nodules are podosome-like structures dependent on Wiskott–Aldrich syndrome protein and ARP2/3 complex

The actin nodule is a novel F-actin structure present in platelets during early spreading. However, only limited detail is known regarding nodule organization and function. Here we use electron microscopy, SIM and dSTORM super-resolution, and live-cell TIRF microscopy to characterize the structural...

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Detalles Bibliográficos
Autores principales: Poulter, Natalie S., Pollitt, Alice Y., Davies, Amy, Malinova, Dessislava, Nash, Gerard B., Hannon, Mike J., Pikramenou, Zoe, Rappoport, Joshua Z., Hartwig, John H., Owen, Dylan M., Thrasher, Adrian J., Watson, Stephen P., Thomas, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458878/
https://www.ncbi.nlm.nih.gov/pubmed/26028144
http://dx.doi.org/10.1038/ncomms8254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458878/
https://www.ncbi.nlm.nih.gov/pubmed/26028144
http://dx.doi.org/10.1038/ncomms8254

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