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Following the intersubunit conformation of the ribosome during translation in real time

We report the direct observation of conformational rearrangements of the ribosome during multiple rounds of elongation. Using single-molecule fluorescence resonance energy transfer, we monitor the intersubunit conformation of the ribosome – in real time – as it proceeds from codon to codon. During e...

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Detalles Bibliográficos
Autores principales: Aitken, Colin Echeverría, Puglisi, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459212/
https://www.ncbi.nlm.nih.gov/pubmed/20562856
http://dx.doi.org/10.1038/nsmb.1828