Cargando…
Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models
Gentamicin may cause acute kidney injury. The pathogenesis of gentamicin nephrotoxicity is unclear. Autophagy is a highly conserved physiological process involved in removing damaged or aged biological macromolecules and organelles from the cytoplasm. The role of autophagy in the pathogenesis of gen...
Autores principales: | Cui, Jing, Bai, Xue-Yuan, Sun, Xuefeng, Cai, Guangyan, Hong, Quan, Ding, Rui, Chen, Xiangmei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459224/ https://www.ncbi.nlm.nih.gov/pubmed/26052900 http://dx.doi.org/10.1038/srep11256 |
Ejemplares similares
-
N-Acetylcysteine Ameliorates Gentamicin-Induced Nephrotoxicity by Enhancing Autophagy and Reducing Oxidative Damage in Miniature Pigs
por: Cui, Jing, et al.
Publicado: (2019) -
Mitochondrial Autophagy Involving Renal Injury and Aging Is Modulated by Caloric Intake in Aged Rat Kidneys
por: Cui, Jing, et al.
Publicado: (2013) -
Rapamycin Upregulates Autophagy by Inhibiting the mTOR-ULK1 Pathway, Resulting in Reduced Podocyte Injury
por: Wu, Lingling, et al.
Publicado: (2013) -
Primary cilium in kidney development, function and disease
por: Bai, Yunfeng, et al.
Publicado: (2022) -
Renal primary cilia lengthen in the progression of diabetic kidney disease
por: Bai, Yunfeng, et al.
Publicado: (2022)