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Crystal structure of 2,2-dimethyl-N-(5-methylpyridin-2-yl)propanamide
There are two molecules in the asymmetric unit of the title compound, C(11)H(16)N(2)O. The pyridine rings and amide groups overlap almost perfectly (r.m.s. overlay fit = 0.053 Å), but the tertiary butyl groups have different orientations: in one molecule, one of the methyl C atoms is syn to the am...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459364/ https://www.ncbi.nlm.nih.gov/pubmed/26090202 http://dx.doi.org/10.1107/S2056989015009378 |
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author | El-Hiti, Gamal A. Smith, Keith Hegazy, Amany S. Alanazi, Saud A. Kariuki, Benson M. |
author_facet | El-Hiti, Gamal A. Smith, Keith Hegazy, Amany S. Alanazi, Saud A. Kariuki, Benson M. |
author_sort | El-Hiti, Gamal A. |
collection | PubMed |
description | There are two molecules in the asymmetric unit of the title compound, C(11)H(16)N(2)O. The pyridine rings and amide groups overlap almost perfectly (r.m.s. overlay fit = 0.053 Å), but the tertiary butyl groups have different orientations: in one molecule, one of the methyl C atoms is syn to the amide O atom [O—C—C—C = −0.8 (3)°] and in the other the equivalent torsion angle is 31.0 (2)°. In the crystal, the two independent molecules are linked by a pair of N—H⋯N hydrogen bonds in the form of an R (2) (2)(8) loop to form a dimer. A C—H⋯O interaction connects the dimers into [100] chains. |
format | Online Article Text |
id | pubmed-4459364 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-44593642015-06-18 Crystal structure of 2,2-dimethyl-N-(5-methylpyridin-2-yl)propanamide El-Hiti, Gamal A. Smith, Keith Hegazy, Amany S. Alanazi, Saud A. Kariuki, Benson M. Acta Crystallogr E Crystallogr Commun Data Reports There are two molecules in the asymmetric unit of the title compound, C(11)H(16)N(2)O. The pyridine rings and amide groups overlap almost perfectly (r.m.s. overlay fit = 0.053 Å), but the tertiary butyl groups have different orientations: in one molecule, one of the methyl C atoms is syn to the amide O atom [O—C—C—C = −0.8 (3)°] and in the other the equivalent torsion angle is 31.0 (2)°. In the crystal, the two independent molecules are linked by a pair of N—H⋯N hydrogen bonds in the form of an R (2) (2)(8) loop to form a dimer. A C—H⋯O interaction connects the dimers into [100] chains. International Union of Crystallography 2015-05-23 /pmc/articles/PMC4459364/ /pubmed/26090202 http://dx.doi.org/10.1107/S2056989015009378 Text en © El-Hiti et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Data Reports El-Hiti, Gamal A. Smith, Keith Hegazy, Amany S. Alanazi, Saud A. Kariuki, Benson M. Crystal structure of 2,2-dimethyl-N-(5-methylpyridin-2-yl)propanamide |
title | Crystal structure of 2,2-dimethyl-N-(5-methylpyridin-2-yl)propanamide |
title_full | Crystal structure of 2,2-dimethyl-N-(5-methylpyridin-2-yl)propanamide |
title_fullStr | Crystal structure of 2,2-dimethyl-N-(5-methylpyridin-2-yl)propanamide |
title_full_unstemmed | Crystal structure of 2,2-dimethyl-N-(5-methylpyridin-2-yl)propanamide |
title_short | Crystal structure of 2,2-dimethyl-N-(5-methylpyridin-2-yl)propanamide |
title_sort | crystal structure of 2,2-dimethyl-n-(5-methylpyridin-2-yl)propanamide |
topic | Data Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459364/ https://www.ncbi.nlm.nih.gov/pubmed/26090202 http://dx.doi.org/10.1107/S2056989015009378 |
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