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D'oh! Genes and Environment Cause Crohn's Disease
Information obtained from genome-wide association studies has cracked open the biology of common chronic diseases by identifying genes that predispose individuals to these disorders. Cadwell et al. (2010) now demonstrate that a viral infection, a toxic insult to the gut, commensal bacteria, and a Cr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cell Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459541/ https://www.ncbi.nlm.nih.gov/pubmed/20602995 http://dx.doi.org/10.1016/j.cell.2010.06.015 |
| Sumario: | Information obtained from genome-wide association studies has cracked open the biology of common chronic diseases by identifying genes that predispose individuals to these disorders. Cadwell et al. (2010) now demonstrate that a viral infection, a toxic insult to the gut, commensal bacteria, and a Crohn's disease susceptibility gene collude to cause inflammatory disease in the mouse gut. |
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