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D'oh! Genes and Environment Cause Crohn's Disease
Information obtained from genome-wide association studies has cracked open the biology of common chronic diseases by identifying genes that predispose individuals to these disorders. Cadwell et al. (2010) now demonstrate that a viral infection, a toxic insult to the gut, commensal bacteria, and a Cr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459541/ https://www.ncbi.nlm.nih.gov/pubmed/20602995 http://dx.doi.org/10.1016/j.cell.2010.06.015 |
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author | Todd, John A. |
author_facet | Todd, John A. |
author_sort | Todd, John A. |
collection | PubMed |
description | Information obtained from genome-wide association studies has cracked open the biology of common chronic diseases by identifying genes that predispose individuals to these disorders. Cadwell et al. (2010) now demonstrate that a viral infection, a toxic insult to the gut, commensal bacteria, and a Crohn's disease susceptibility gene collude to cause inflammatory disease in the mouse gut. |
format | Online Article Text |
id | pubmed-4459541 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Cell Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-44595412015-06-16 D'oh! Genes and Environment Cause Crohn's Disease Todd, John A. Cell Preview Information obtained from genome-wide association studies has cracked open the biology of common chronic diseases by identifying genes that predispose individuals to these disorders. Cadwell et al. (2010) now demonstrate that a viral infection, a toxic insult to the gut, commensal bacteria, and a Crohn's disease susceptibility gene collude to cause inflammatory disease in the mouse gut. Cell Press 2010-06-25 /pmc/articles/PMC4459541/ /pubmed/20602995 http://dx.doi.org/10.1016/j.cell.2010.06.015 Text en © 2010 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Preview Todd, John A. D'oh! Genes and Environment Cause Crohn's Disease |
title | D'oh! Genes and Environment Cause Crohn's Disease |
title_full | D'oh! Genes and Environment Cause Crohn's Disease |
title_fullStr | D'oh! Genes and Environment Cause Crohn's Disease |
title_full_unstemmed | D'oh! Genes and Environment Cause Crohn's Disease |
title_short | D'oh! Genes and Environment Cause Crohn's Disease |
title_sort | d'oh! genes and environment cause crohn's disease |
topic | Preview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459541/ https://www.ncbi.nlm.nih.gov/pubmed/20602995 http://dx.doi.org/10.1016/j.cell.2010.06.015 |
work_keys_str_mv | AT toddjohna dohgenesandenvironmentcausecrohnsdisease |