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D'oh! Genes and Environment Cause Crohn's Disease

Information obtained from genome-wide association studies has cracked open the biology of common chronic diseases by identifying genes that predispose individuals to these disorders. Cadwell et al. (2010) now demonstrate that a viral infection, a toxic insult to the gut, commensal bacteria, and a Cr...

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Detalles Bibliográficos
Autor principal: Todd, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459541/
https://www.ncbi.nlm.nih.gov/pubmed/20602995
http://dx.doi.org/10.1016/j.cell.2010.06.015
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author_facet Todd, John A.
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description Information obtained from genome-wide association studies has cracked open the biology of common chronic diseases by identifying genes that predispose individuals to these disorders. Cadwell et al. (2010) now demonstrate that a viral infection, a toxic insult to the gut, commensal bacteria, and a Crohn's disease susceptibility gene collude to cause inflammatory disease in the mouse gut.
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spelling pubmed-44595412015-06-16 D'oh! Genes and Environment Cause Crohn's Disease Todd, John A. Cell Preview Information obtained from genome-wide association studies has cracked open the biology of common chronic diseases by identifying genes that predispose individuals to these disorders. Cadwell et al. (2010) now demonstrate that a viral infection, a toxic insult to the gut, commensal bacteria, and a Crohn's disease susceptibility gene collude to cause inflammatory disease in the mouse gut. Cell Press 2010-06-25 /pmc/articles/PMC4459541/ /pubmed/20602995 http://dx.doi.org/10.1016/j.cell.2010.06.015 Text en © 2010 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Preview
Todd, John A.
D'oh! Genes and Environment Cause Crohn's Disease
title D'oh! Genes and Environment Cause Crohn's Disease
title_full D'oh! Genes and Environment Cause Crohn's Disease
title_fullStr D'oh! Genes and Environment Cause Crohn's Disease
title_full_unstemmed D'oh! Genes and Environment Cause Crohn's Disease
title_short D'oh! Genes and Environment Cause Crohn's Disease
title_sort d'oh! genes and environment cause crohn's disease
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459541/
https://www.ncbi.nlm.nih.gov/pubmed/20602995
http://dx.doi.org/10.1016/j.cell.2010.06.015
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