Applications of calixarenes in cancer chemotherapy: facts and perspectives

Research on the therapeutic applications of calixarene derivatives is an emerging area of interest. The anticancer activity of various functionalized calixarenes has been reported by several research groups. Due to their superior geometric shape, calixarenes can accommodate drug molecules by forming...

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Detalles Bibliográficos
Autores principales: Yousaf, Ali, Hamid, Shafida Abd, Bunnori, Noraslinda M, Ishola, AA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459628/
https://www.ncbi.nlm.nih.gov/pubmed/26082613
http://dx.doi.org/10.2147/DDDT.S83213
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author Yousaf, Ali
Hamid, Shafida Abd
Bunnori, Noraslinda M
Ishola, AA
author_facet Yousaf, Ali
Hamid, Shafida Abd
Bunnori, Noraslinda M
Ishola, AA
author_sort Yousaf, Ali
collection PubMed
description Research on the therapeutic applications of calixarene derivatives is an emerging area of interest. The anticancer activity of various functionalized calixarenes has been reported by several research groups. Due to their superior geometric shape, calixarenes can accommodate drug molecules by forming inclusion complexes. Controlled release of anticancer drugs by calixarenes might help in targeted chemotherapy. This review summarizes the anticancer potential of the calixarenes and their drug loading properties. The potential use of calixarenes in chemoradiotherapy is also highlighted in brief.
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spelling pubmed-44596282015-06-16 Applications of calixarenes in cancer chemotherapy: facts and perspectives Yousaf, Ali Hamid, Shafida Abd Bunnori, Noraslinda M Ishola, AA Drug Des Devel Ther Review Research on the therapeutic applications of calixarene derivatives is an emerging area of interest. The anticancer activity of various functionalized calixarenes has been reported by several research groups. Due to their superior geometric shape, calixarenes can accommodate drug molecules by forming inclusion complexes. Controlled release of anticancer drugs by calixarenes might help in targeted chemotherapy. This review summarizes the anticancer potential of the calixarenes and their drug loading properties. The potential use of calixarenes in chemoradiotherapy is also highlighted in brief. Dove Medical Press 2015-06-02 /pmc/articles/PMC4459628/ /pubmed/26082613 http://dx.doi.org/10.2147/DDDT.S83213 Text en © 2015 Yousaf et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Yousaf, Ali
Hamid, Shafida Abd
Bunnori, Noraslinda M
Ishola, AA
Applications of calixarenes in cancer chemotherapy: facts and perspectives
title Applications of calixarenes in cancer chemotherapy: facts and perspectives
title_full Applications of calixarenes in cancer chemotherapy: facts and perspectives
title_fullStr Applications of calixarenes in cancer chemotherapy: facts and perspectives
title_full_unstemmed Applications of calixarenes in cancer chemotherapy: facts and perspectives
title_short Applications of calixarenes in cancer chemotherapy: facts and perspectives
title_sort applications of calixarenes in cancer chemotherapy: facts and perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459628/
https://www.ncbi.nlm.nih.gov/pubmed/26082613
http://dx.doi.org/10.2147/DDDT.S83213
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