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Association of HSD11B1 polymorphic variants and adipose tissue gene expression with metabolic syndrome, obesity and type 2 diabetes mellitus: a systematic review
The HSD11B1 gene is highly expressed in abdominal adipose tissue, and the enzyme it encodes catalyzes the interconversion of inactive cortisone to hormonally active cortisol. Genetic abnormalities of HSD11B1 have been associated with the development of abnormal glucose metabolism and body fat distri...
Autores principales: | do Nascimento, Filipe Valvassori, Piccoli, Vanessa, Beer, Mayara Abichequer, von Frankenberg, Anize Delfino, Crispim, Daisy, Gerchman, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459686/ https://www.ncbi.nlm.nih.gov/pubmed/26056536 http://dx.doi.org/10.1186/s13098-015-0036-1 |
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