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Overexpression of Lamin B Receptor Results in Impaired Skin Differentiation
Hutchinson-Gilford progeria syndrome (HGPS) is a rare segmental progeroid disorder commonly caused by a point mutation in the LMNA gene that results in the increased activation of an intra-exonic splice site and the production of a truncated lamin A protein, named progerin. In our previous work, ind...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459694/ https://www.ncbi.nlm.nih.gov/pubmed/26053873 http://dx.doi.org/10.1371/journal.pone.0128917 |