Spine Pruning Drives Antipsychotic-sensitive Locomotion via Circuit Control of Striatal Dopamine

Psychiatric and neurodevelopmental disorders may arise from anomalies in long-range neuronal connectivity downstream of pathologies in dendritic spines. However, the mechanisms that may link spine pathology to circuit abnormalities relevant to atypical behavior remain unknown. Using a mouse model to...

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Detalles Bibliográficos
Autores principales: Kim, Il Hwan, Rossi, Mark A., Aryal, Dipendra K., Racz, Bence, Kim, Namsoo, Uezu, Akiyoshi, Wang, Fan, Wetsel, William C., Weinberg, Richard J., Yin, Henry, Soderling, Scott H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459733/
https://www.ncbi.nlm.nih.gov/pubmed/25938885
http://dx.doi.org/10.1038/nn.4015

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