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Divergent androgen regulation of unfolded protein response pathways drives prostate cancer
The unfolded protein response (UPR) is a homeostatic mechanism to maintain endoplasmic reticulum (ER) function. The UPR is activated by various physiological conditions as well as in disease states, such as cancer. As androgens regulate secretion and development of the normal prostate and drive pros...
Autores principales: | Sheng, Xia, Arnoldussen, Yke Jildouw, Storm, Margrethe, Tesikova, Martina, Nenseth, Hatice Zeynep, Zhao, Sen, Fazli, Ladan, Rennie, Paul, Risberg, Bjørn, Wæhre, Håkon, Danielsen, Håvard, Mills, Ian G, Jin, Yang, Hotamisligil, Gökhan, Saatcioglu, Fahri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459818/ https://www.ncbi.nlm.nih.gov/pubmed/25864123 http://dx.doi.org/10.15252/emmm.201404509 |
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