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Variation in Gamma-Globin Expression before and after Induction with Hydroxyurea Associated with BCL11A, KLF1 and TAL1

The molecular mechanisms governing γ-globin expression in a subset of fetal hemoglobin (α2γ2: HbF) expressing red blood cells (F-cells) and the mechanisms underlying the variability of response to hydroxyurea induced γ-globin expression in the treatment of sickle cell disease are not completely unde...

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Detalles Bibliográficos
Autores principales:	Grieco, Amanda J., Billett, Henny H., Green, Nancy S., Driscoll, M. Catherine, Bouhassira, Eric E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459969/ https://www.ncbi.nlm.nih.gov/pubmed/26053062 http://dx.doi.org/10.1371/journal.pone.0129431

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