Cargando…

On the Use of Optically Stimulated Luminescent Dosimeter for Surface Dose Measurement during Radiotherapy

This study was carried out to investigate the suitability of using the optically stimulated luminescence dosimeter (OSLD) in measuring surface dose during radiotherapy. The water equivalent depth (WED) of the OSLD was first determined by comparing the surface dose measured using the OSLD with the pe...

Descripción completa

Detalles Bibliográficos
Autores principales: Yusof, Fasihah Hanum, Ung, Ngie Min, Wong, Jeannie Hsiu Ding, Jong, Wei Loong, Ath, Vannyat, Phua, Vincent Chee Ee, Heng, Siew Ping, Ng, Kwan Hoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459977/
https://www.ncbi.nlm.nih.gov/pubmed/26052690
http://dx.doi.org/10.1371/journal.pone.0128544
_version_ 1782375295694667776
author Yusof, Fasihah Hanum
Ung, Ngie Min
Wong, Jeannie Hsiu Ding
Jong, Wei Loong
Ath, Vannyat
Phua, Vincent Chee Ee
Heng, Siew Ping
Ng, Kwan Hoong
author_facet Yusof, Fasihah Hanum
Ung, Ngie Min
Wong, Jeannie Hsiu Ding
Jong, Wei Loong
Ath, Vannyat
Phua, Vincent Chee Ee
Heng, Siew Ping
Ng, Kwan Hoong
author_sort Yusof, Fasihah Hanum
collection PubMed
description This study was carried out to investigate the suitability of using the optically stimulated luminescence dosimeter (OSLD) in measuring surface dose during radiotherapy. The water equivalent depth (WED) of the OSLD was first determined by comparing the surface dose measured using the OSLD with the percentage depth dose at the buildup region measured using a Markus ionization chamber. Surface doses were measured on a solid water phantom using the OSLD and compared against the Markus ionization chamber and Gafchromic EBT3 film measurements. The effect of incident beam angles on surface dose was also studied. The OSLD was subsequently used to measure surface dose during tangential breast radiotherapy treatments in a phantom study and in the clinical measurement of 10 patients. Surface dose to the treated breast or chest wall, and on the contralateral breast were measured. The WED of the OSLD was found to be at 0.4 mm. For surface dose measurement on a solid water phantom, the Markus ionization chamber measured 15.95% for 6 MV photon beam and 12.64% for 10 MV photon beam followed by EBT3 film (23.79% and 17.14%) and OSLD (37.77% and 25.38%). Surface dose increased with the increase of the incident beam angle. For phantom and patient breast surface dose measurement, the response of the OSLD was higher than EBT3 film. The in-vivo measurements were also compared with the treatment planning system predicted dose. The OSLD measured higher dose values compared to dose at the surface (Hp(0.0)) by a factor of 2.37 for 6 MV and 2.01 for 10 MV photon beams, respectively. The measurement of absorbed dose at the skin depth of 0.4 mm by the OSLD can still be a useful tool to assess radiation effects on the skin dermis layer. This knowledge can be used to prevent and manage potential acute skin reaction and late skin toxicity from radiotherapy treatments.
format Online
Article
Text
id pubmed-4459977
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-44599772015-06-16 On the Use of Optically Stimulated Luminescent Dosimeter for Surface Dose Measurement during Radiotherapy Yusof, Fasihah Hanum Ung, Ngie Min Wong, Jeannie Hsiu Ding Jong, Wei Loong Ath, Vannyat Phua, Vincent Chee Ee Heng, Siew Ping Ng, Kwan Hoong PLoS One Research Article This study was carried out to investigate the suitability of using the optically stimulated luminescence dosimeter (OSLD) in measuring surface dose during radiotherapy. The water equivalent depth (WED) of the OSLD was first determined by comparing the surface dose measured using the OSLD with the percentage depth dose at the buildup region measured using a Markus ionization chamber. Surface doses were measured on a solid water phantom using the OSLD and compared against the Markus ionization chamber and Gafchromic EBT3 film measurements. The effect of incident beam angles on surface dose was also studied. The OSLD was subsequently used to measure surface dose during tangential breast radiotherapy treatments in a phantom study and in the clinical measurement of 10 patients. Surface dose to the treated breast or chest wall, and on the contralateral breast were measured. The WED of the OSLD was found to be at 0.4 mm. For surface dose measurement on a solid water phantom, the Markus ionization chamber measured 15.95% for 6 MV photon beam and 12.64% for 10 MV photon beam followed by EBT3 film (23.79% and 17.14%) and OSLD (37.77% and 25.38%). Surface dose increased with the increase of the incident beam angle. For phantom and patient breast surface dose measurement, the response of the OSLD was higher than EBT3 film. The in-vivo measurements were also compared with the treatment planning system predicted dose. The OSLD measured higher dose values compared to dose at the surface (Hp(0.0)) by a factor of 2.37 for 6 MV and 2.01 for 10 MV photon beams, respectively. The measurement of absorbed dose at the skin depth of 0.4 mm by the OSLD can still be a useful tool to assess radiation effects on the skin dermis layer. This knowledge can be used to prevent and manage potential acute skin reaction and late skin toxicity from radiotherapy treatments. Public Library of Science 2015-06-08 /pmc/articles/PMC4459977/ /pubmed/26052690 http://dx.doi.org/10.1371/journal.pone.0128544 Text en © 2015 Yusof et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Yusof, Fasihah Hanum
Ung, Ngie Min
Wong, Jeannie Hsiu Ding
Jong, Wei Loong
Ath, Vannyat
Phua, Vincent Chee Ee
Heng, Siew Ping
Ng, Kwan Hoong
On the Use of Optically Stimulated Luminescent Dosimeter for Surface Dose Measurement during Radiotherapy
title On the Use of Optically Stimulated Luminescent Dosimeter for Surface Dose Measurement during Radiotherapy
title_full On the Use of Optically Stimulated Luminescent Dosimeter for Surface Dose Measurement during Radiotherapy
title_fullStr On the Use of Optically Stimulated Luminescent Dosimeter for Surface Dose Measurement during Radiotherapy
title_full_unstemmed On the Use of Optically Stimulated Luminescent Dosimeter for Surface Dose Measurement during Radiotherapy
title_short On the Use of Optically Stimulated Luminescent Dosimeter for Surface Dose Measurement during Radiotherapy
title_sort on the use of optically stimulated luminescent dosimeter for surface dose measurement during radiotherapy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459977/
https://www.ncbi.nlm.nih.gov/pubmed/26052690
http://dx.doi.org/10.1371/journal.pone.0128544
work_keys_str_mv AT yusoffasihahhanum ontheuseofopticallystimulatedluminescentdosimeterforsurfacedosemeasurementduringradiotherapy
AT ungngiemin ontheuseofopticallystimulatedluminescentdosimeterforsurfacedosemeasurementduringradiotherapy
AT wongjeanniehsiuding ontheuseofopticallystimulatedluminescentdosimeterforsurfacedosemeasurementduringradiotherapy
AT jongweiloong ontheuseofopticallystimulatedluminescentdosimeterforsurfacedosemeasurementduringradiotherapy
AT athvannyat ontheuseofopticallystimulatedluminescentdosimeterforsurfacedosemeasurementduringradiotherapy
AT phuavincentcheeee ontheuseofopticallystimulatedluminescentdosimeterforsurfacedosemeasurementduringradiotherapy
AT hengsiewping ontheuseofopticallystimulatedluminescentdosimeterforsurfacedosemeasurementduringradiotherapy
AT ngkwanhoong ontheuseofopticallystimulatedluminescentdosimeterforsurfacedosemeasurementduringradiotherapy