Pervasive Genotypic Mosaicism in Founder Mice Derived from Genome Editing through Pronuclear Injection

Genome editing technologies, especially the Cas9/CRISPR system, have revolutionized biomedical research over the past several years. Generation of novel alleles has been simplified to unprecedented levels, allowing for rapid expansion of available genetic tool kits for researchers. However, the issu...

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Detalles Bibliográficos
Autores principales: Oliver, Daniel, Yuan, Shuiqiao, McSwiggin, Hayden, Yan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459985/
https://www.ncbi.nlm.nih.gov/pubmed/26053263
http://dx.doi.org/10.1371/journal.pone.0129457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459985/
https://www.ncbi.nlm.nih.gov/pubmed/26053263
http://dx.doi.org/10.1371/journal.pone.0129457

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