Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat

BACKGROUND: Adeno associated virus (AAV) is well known for its ability to deliver transgenes to retina and to mediate improvements in animal models and patients with inherited retinal disease. Although the field is less advanced, there is growing interest in AAV’s ability to target cells of the ante...

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Detalles Bibliográficos
Autores principales: Bogner, Barbara, Boye, Sanford L., Min, Seok Hong, Peterson, James J., Ruan, Qing, Zhang, Zhonghong, Reitsamer, Herbert A., Hauswirth, William W., Boye, Shannon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460001/
https://www.ncbi.nlm.nih.gov/pubmed/26052939
http://dx.doi.org/10.1371/journal.pone.0128759

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